Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer
… DNA was captured on a Qiagen Genomic Tip column, washed, and eluted by gravity flow. …
any platform-specific bias, we ran this analysis on both WGS and genome-wide CNV array …
any platform-specific bias, we ran this analysis on both WGS and genome-wide CNV array …
[HTML][HTML] Extended kinship analysis of historical remains using SNP capture
EM Gorden, EM Greytak, K Sturk-Andreaggi… - Forensic Science …, 2022 - Elsevier
… Family reference samples were genotyped using a standard SNP microarray. … using
microarray platforms (ie high quality FRS). The first SNP capture panel contained 24,999 genomic …
microarray platforms (ie high quality FRS). The first SNP capture panel contained 24,999 genomic …
[HTML][HTML] Genomic signatures of past and present chromosomal instability in Barrett's esophagus and early esophageal adenocarcinoma
… laser capture microdissection and subjected to whole-genome … Platform at the Broad Institute,
including base-quality score … for SNP array data 60 , whole-genome sequencing 61 , and …
including base-quality score … for SNP array data 60 , whole-genome sequencing 61 , and …
[HTML][HTML] Enhanced clinical assessment of hematologic malignancies through routine paired tumor and normal sequencing
… DNA using a hybridization capture-based next generation … ability of mutation signature
analysis from targeted sequencing of … by clinically validated SNP array platforms. MSK-IMPACT …
analysis from targeted sequencing of … by clinically validated SNP array platforms. MSK-IMPACT …
[HTML][HTML] AI applications in functional genomics
… low-dimensional space trying to maintain the variance as much as possible[19]. One of the
main limits of this method is that it can capture only linear correlations between variables. To …
main limits of this method is that it can capture only linear correlations between variables. To …
Molecular, Genetic, and Other Omics Data
… of a small number of anonymous donors. … of the number of times each sequence variant has
been observed in each of … These focus on capturing the representation of various genes in a …
been observed in each of … These focus on capturing the representation of various genes in a …
[HTML][HTML] Detecting copy number variation in next generation sequencing data from diagnostic gene panels
AK Singh, MF Olsen, LAS Lavik, T Vold, F Drabløs… - … Medical Genomics, 2021 - Springer
… labs most commonly use aCGH/SNP microarray and MLPA. … be sequenced using the same
batch of target capturing kit as … testing with respect to anonymity and concluded that the CNV…
batch of target capturing kit as … testing with respect to anonymity and concluded that the CNV…
[HTML][HTML] Pan-genome analysis of 13 Malus accessions reveals structural and sequence variations associated with fruit traits
T Wang, S Duan, C Xu, Y Wang, X Zhang, X Xu… - Nature …, 2023 - nature.com
… sequencing and chromosome conformation capture (Hi-C) … the GS genome assembly reached
the “gold standard” level (LAI … were constructed and sequenced on NovaSeq platform. The …
the “gold standard” level (LAI … were constructed and sequenced on NovaSeq platform. The …
[PDF][PDF] DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse
… We have developed a mouse DNA methylation array that … Notably, we find that tissue-specific
methylation signatures … assay platform, as observed in our human array studies,20,99 …
methylation signatures … assay platform, as observed in our human array studies,20,99 …
[PDF][PDF] Computing genomic signatures using de bruijn chains
… regions of conserved or divergent gene order. Genomic signatures work by capturing one or
more such features … We also thank the two anonymous reviewers for their careful feedback. …
more such features … We also thank the two anonymous reviewers for their careful feedback. …